The Associated Press (AP) asked US federal departments to show them the evidence used for producing the guidelines, such as the surgeon general’s, which recommend flossing. When the government responded that the recommendations weren’t based on research, AP decided to perform its own study by looking for research from the past decade, and wrote their article which focused on 25 studies that “generally compared the use of a toothbrush with the combination of toothbrushes and floss.”
The conclusion of AP’s study, contained in their article, is that the evidence for flossing is “weak, very unreliable,” of “very low” quality, and carries “a moderate to large potential for bias.” (source)
So, to sum it up, none of the 25 studies (limited to those conducted in the past decade) which AP reviewed provided strong evidence for the recommendations which have been in place several decades
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